Authors:

Ketut Widyani Astuti, Yeyet C. Sumirtapura, Ni Nyoman Wiwik S.

Abstract:

“Diffusion of sodium diclofenac in Methocel 400 gel at various pH has been studied. Diffusion test was performed in diffusion cells with artificial membranes of Whatman no.1 filter paper which was immersed in Spangler solution. Measurement of active ingredient concentration that diffuses was performed using UV spectrophotometer at a wavelength of 277 nm.The results showed that highest diffusion of diclofenac sodium occured at pH 7 with a mean percentage of diclofenac sodium diffuses after 240 minutes of 56,88 + 13,70%. The mean percentage of diclofenac sodium which diffuses from the gel Methocel 400 at pH 6 after 240 minutes was 30,39 + 1,08% while that from the Methocel 400 gel at pH 8 was 46,84 + 6,24%.”

Keywords

Keyword Not Available

Downloads:

Download data is not yet available.

References

References Not Available

PDF:

https://jurnal.harianregional.com/jchem/full-2860

Published

2021-11-09

How To Cite

WIDYANI ASTUTI, Ketut; SUMIRTAPURA, Yeyet C.; WIWIK S., Ni Nyoman. DIFUSI NATRIUM DIKLOFENAK DALAM GEL METHOCEL 400 PADA BERBAGAI pH.Jurnal Kimia (Journal of Chemistry), [S.l.], nov. 2012. ISSN 2599-2740. Available at: https://jurnal.harianregional.com/jchem/id-2860. Date accessed: 08 Jul. 2024.

Citation Format

ABNT, APA, BibTeX, CBE, EndNote - EndNote format (Macintosh & Windows), MLA, ProCite - RIS format (Macintosh & Windows), RefWorks, Reference Manager - RIS format (Windows only), Turabian

Issue

Vol. 6, No. 1 Januari 2012

Section

Articles

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License