Authors:

Hesty Rohmatul Fajri, Raden Argarini, Choesnan Effendi

Abstract:

“Submaximal activity leads to oxidative stress that causes cellular damage, including platelet. Glutathione as a potential antioxidant has cellular protective effect. The purpose of this research was to analize the effect of glutathione pre submaximal exercise on platelet count and bleeding time. The study used separate post test only control group design with 28 male rats (Rattus norvegicus, Wistar strain) which were divided into four groups : P1(6) without intervention; P2(7), P3(8), and P4(7) with administration of placebo (aquabidest), glutathione 54 mg/kgBB, and glutathione 108 mg/kgBB intraperitoneally for each group that were given 5 times, continued with submaximal exercise (swimming with 4% of weight load). The result of ANOVA and LSD test showed that submaximal exercise had tendency to decrease platelet count (p=0,407; not significant) and prolonged bleeding time (p=0,017). Glutathione pre submaximal exercise had tendency to increase platelet count (p=0,407; not significant) and shortened bleeding time (p=0,017). Glutathione with a dose of 54 mg/kg had protective effect on platelet better than a dose of 108 mg/kg. In conclusion, the administration of glutathione pre submaximal exercise has protective effect on platelet in male rats (Rattus norvegicus).”

Keywords

Keyword Not Available

Downloads:

Download data is not yet available.

References

References Not Available

PDF:

https://jurnal.harianregional.com/sport/full-11872

Published

2021-11-09

How To Cite

FAJRI, Hesty Rohmatul; ARGARINI, Raden; EFFENDI, Choesnan. PENGARUH PEMBERIAN GLUTATHIONE PRA LATIHAN SUBMAKSIMAL TERHADAP JUMLAH TROMBOSIT DAN MASA PERDARAHAN : STUDI EKSPERIMENTAL PADA HEWAN COBA.Sport and Fitness Journal, [S.l.], jan. 2015. ISSN 2654-9182. Available at: https://jurnal.harianregional.com/sport/id-11872. Date accessed: 28 Aug. 2025.

Citation Format

ABNT, APA, BibTeX, CBE, EndNote - EndNote format (Macintosh & Windows), MLA, ProCite - RIS format (Macintosh & Windows), RefWorks, Reference Manager - RIS format (Windows only), Turabian

Issue

Volume 3, No.1, 2015

Section

Articles

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License