Authors:

Dewa Ayu Made Adnya Swari, Ni Putu Udayana A, Ni Made Dharma Shantini S

Abstract:

“Background: Hand sanitizers contain 62% alcohol, softener and moisturizer. High alcohol content is able to irritate and make hands dry. A suitable moisturizer is needed for this preparation. Objective: The aim of this study is to evaluate the physical quality of gel hand sanitizer formulation of Ocimum tenuiflorum with CMC-Na as a gelling agent at a concentration of 0.5% and 1% CMC-Na. Methods: Data were collected at week-0,1,2,3,4, and replication is performed three times at each concentration of each measurement. The test results of the spread and adhesion data analysis using SPSS with a 95% confidence level. Results: Dispersive power and adhesion showed no significant difference (p <0.05) at week 0 and week 4 means second-hand sanitizer gel formulation concentration is not stable. Gel hand sanitizer leaves of Tulasi (Ocimum tenuiflorum) at a concentration of 1% CMC-Na stable from week 0 to week 3, while the concentration of 0.5% CMC-Na change at week 2. Gel hand sanitizer leaves of Tulasi (Ocimum tenuiflorum) with a gelling agent CMC-Na should need to be titrated. Conclusion: Gel hand sanitizer leaves of Tulasi (Ocimum tenuiflorum) that use concentrations of 1% CMC-Na as a gelling agent have a physical quality that is more stable than the organoleptic test concentration of 0.5% CMC-Na. Keywords: Hand sanitizer, Ocimum tenuiflorum L., CMC-Na, Physical quality evaluation”

Keywords

Hand sanitizer, Ocimum tenuiflorum L., CMC-Na, Physical quality evaluation

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PDF:

https://jurnal.harianregional.com/jpsa/full-60490

Published

2020-06-18

How To Cite

SWARI, Dewa Ayu Made Adnya; UDAYANA A, Ni Putu; SHANTINI S, Ni Made Dharma. STABILITY COMPARISON OF TULASI (Ocimum tenuiflorum L.) LEAF GEL HAND SANITIZER USING 0.5% AND 1% CMC-Na.Journal Pharmaceutical Science and Application, [S.l.], v. 2, n. 1, p. 23-27, june 2020. ISSN 2301-7708. Available at: https://jurnal.harianregional.com/jpsa/id-60490. Date accessed: 28 Aug. 2025. doi:https://doi.org/10.24843/JPSA.2020.v02.i01.p04.

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Issue

Vol 2 No 1 (2020): Journal Pharmaceutical Science and Application

Section

Articles

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