Authors:

Tjok Istri Anom S, I Dewa Nyoman Wibawa

Abstract:

“Liver Þ brosis is the excessive accumulation of extracellular matrix proteins including collagen that occurs in most typesof chronic liver. The gold standard to assess disease severity of liver Þ brosis is liver biopsy, despite noninvasive methodsavailable today. A noninvasive tool (Þ bro scan) has been developed these days. This tool is similar to ultrasound in assessingliver elasticity. There are three methods frequently used to assess liver Þ brosis, Ishak score, Metavir score, and Desmet/Scheuerstaging system. The principles of antiÞ brotic therapy are: (a) to treat primary disease; (b) to reduce inß ammation responseor to avoid stimulation of stellate cell activation; (c) to reduce stellate cell activation; (d) to neutralize proliferation response,Þ brogenic response, contractic response, and/or stellate cell proinß ammation; (e) to stimulate apoptosis of stellate cell; and (f) toincrease degradation of Þ brotic tissue.”

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PDF:

https://jurnal.harianregional.com/jim/full-3911

Published

2021-11-09

How To Cite

ANOM S, Tjok Istri; WIBAWA, I Dewa Nyoman. PENDEKATAN DIAGNOSIS DAN TERAPI FIBROSIS HATI.journal of internal medicine, [S.l.], nov. 2012. Available at: https://jurnal.harianregional.com/jim/id-3911. Date accessed: 02 Jun. 2025.

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Issue

Vol. 11, No. 1 Januari 2010

Section

Articles

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License