Authors:

Made Putra Sedana, T. Ivone Wulansari

Abstract:

“Myeloproliferative disorder (MPD) represent a group of disease marked by cellular proliferation of one or morehaematologic stem cells which include polycythemia vera, essential thrombocythemia, chronic idiopathic myelofibrosis withmyeloid metaplasia / MMM, hypereosinophillic syndrome / HES, unclassified myeloproliferative disease / U-Mpd, chronicmyelogenous leukemia / CML and chronic neutrophylic leukemia / CNL. The incidence and pathogenesis are still unknown.Chronicity which alterable to aggressive phase become acute leukemia and clonal cytogenetic abnormalities in erythroblast,neutrophyl, basophyl, macrophage, megakaryocytes and B-lymphocytes, but not in fibroblast are characteristics of the disease.Haematopoeisis is marked by autonomically growth and myeloid hyperplasia in bone marrow. Bone marrow aspiration showtrilineage hypercellularity. The complications include thrombotic phenomenon, micro and macrovascular arteries thrombosis,bleeding phenomenon, hypercatabolism and transformation into acute myelogenous leukemia / AML. Pseudocoagulopathy,pseudohyperkalemia, pseudohyperacydphosphatemia, pseudohypoglicemia and pseudohypoxemia can be seen.”

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PDF:

https://jurnal.harianregional.com/jim/full-3814

Published

2021-11-09

How To Cite

PUTRA SEDANA, Made; WULANSARI, T. Ivone. PENYAKIT MIELOPROLIFERATIF.journal of internal medicine, [S.l.], nov. 2012. Available at: https://jurnal.harianregional.com/jim/id-3814. Date accessed: 08 Jul. 2024.

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Issue

Vol. 8, No. 1 Januari 2007

Section

Articles

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License