Authors:

Ayuningtyas Istiqomah, Wahyu Utami

Abstract:

“Supplementation can play a supporting role in COVID-19 patients, one of which is the provision of vitamin D supplementation. This study aims to discuss and examine the existing evidence regarding the effect of vitamin D supplementation in reducing severity and preventing/treating COVID-19. The method used is a literature study from various library sources that can be accessed using the PubMed and Google Scholar databases with the keywords [(“Vitamin D” OR “Vitamin D2” OR “Vitamin D3”) AND (“COVID-19” OR “Coronavirus Disease 2019” OR “SARS CoV 2”)]. Sixty-eight studies met the inclusion and exclusion criteria and are therefore included in this literature review. This study shows that the lower the level of vitamin D in the body, the higher the severity of COVID-19. In addition, the use of vitamin D supplementation has a positive effect on COVID-19 by reducing the risk of being infected with COVID-19, reducing the risk of death, and reducing the severity of COVID-19. This could be because vitamin D can enhance the innate immune system which is the body’s first line of defense against pathogens and regulate the adaptive immune system to reduce cytokine storms, and has a potential protective role against acute respiratory distress syndrome by inhibiting the renin-angiotensin pathway. Therefore, vitamin D supplementation can be used as an additional treatment for COVID-19.”

Keywords

[(“Vitamin D” OR “Vitamin D2” OR “Vitamin D3”) AND (“COVID-19” OR “Coronavirus Disease 2019” OR “SARS CoV 2”)]. Sixty-eight studies met the inclusion and exclusion criteria and are therefore included in this literature review. This study shows that the lower the level of vitamin D in the body, the higher the severity of COVID-19. In addition, the use of vitamin D supplementation has a positive effect on COVID-19 by reducing the risk of being infected with COVID-19, reducing the risk of death, and reducing the severity of COVID-19. This could be because vitamin D can enhance the innate immune system which is the body’s first line of defense against pathogens and regulate the adaptive immune system to reduce cytokine storms, and has a potential protective role against acute respiratory distress syndrome by inhibiting the renin-angiotensin pathway. Therefore, vitamin D supplementation can be used as an additional treatment for COVID-19.

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PDF:

https://jurnal.harianregional.com/jfu/full-89168

Published

2023-08-28

How To Cite

ISTIQOMAH, Ayuningtyas; UTAMI, Wahyu. Kajian Literatur: Suplementasi Vitamin D Mengurangi Tingkat Keparahan serta Mencegah dan Mengobati COVID-19.Jurnal Farmasi Udayana, [S.l.], p. 7-18, aug. 2023. ISSN 2622-4607. Available at: https://jurnal.harianregional.com/jfu/id-89168. Date accessed: 28 Aug. 2025. doi:https://doi.org/10.24843/JFU.2023.v12.i01.p02.

Citation Format

ABNT, APA, BibTeX, CBE, EndNote - EndNote format (Macintosh & Windows), MLA, ProCite - RIS format (Macintosh & Windows), RefWorks, Reference Manager - RIS format (Windows only), Turabian

Issue

Vol. 12, No 1, Tahun 2023

Section

Articles

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License