Authors:

Mahardika Aprilia Iflahah, Ni Made Suaniti, Ida Ayu Raka Astiti Asih

Abstract:

“Urinary level of 8-OHdG in rats after exposure to ethanol and smoke have been investigated for 15 days with TLC-Spectrophotodensitometer. Ethanol and smoke exposure to could increase the number of Reactive Oxygen Species (ROS), which could lead to a state called oxidative stress. 8-OHdG compound is the result of DNA oxidation by ROS in the body in the form of guanine nucleotide. This 8-OHdG is a water-soluble compound excreted in urine easily. In this study, exposure of ethanol and smoke both singly and combined had an effect on the level of 8-OHdG. Urinary level of 8-OHdG in the control group; groups exposed to ethanol, smoke, and ethanol-smoke were (0,00 ± 0,00)%, (0,33 ± 0,08)%, (0,25 ± 0,10)%, and (0,57 ± 0,27)% respectively.”

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PDF:

https://jurnal.harianregional.com/jchem/full-9744

Published

2014-01-01

How To Cite

IFLAHAH, Mahardika Aprilia; SUANITI, Ni Made; RAKA ASTITI ASIH, Ida Ayu. PENENTUAN KADAR 8-HIDROKSI-2’-DEOKSIGUANOSIN (8-OHdG) DALAM URIN TIKUS SETELAH TERPAPAR ETANOL DAN ASAP ROKOK.Jurnal Kimia (Journal of Chemistry), [S.l.], jan. 2014. ISSN 2599-2740. Available at: https://jurnal.harianregional.com/jchem/id-9744. Date accessed: 28 Aug. 2025. doi:https://doi.org/10.24843/JCHEM.2014.v08.i01.p07.

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Issue

Vol. 8, No. 1 Januari 2014

Section

Articles

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