Authors:

Sri Rahayu Santi

Abstract:

“Isolation and identification of active toxic compounds from nyamplung skin bean (Calophyllum inophyllumL). has been carried out. As much as 12,43 g of concentrated methanol extract was resulted from 1.0 kg dry powdernyamplung skin bean that was macerated using methanol. This extract was dissolved into methanol-water (7:3) andthen partitioned with n-hexane and chloroform respectively. The result of toxicity test to both extract showed thatchloroform extract was the most active toxic with LC50 = 239,88 ppmSeparation of chloroform extract using preparative thin layer chromatography (TLC) resulted in F5 fractionsthat was white yellowish as much as 52 mg and LC50 = 151,36 ppm. Infra red and UV-vis spectroscopy wereemployed in order to identify the F5 fraction. The result of identification showed that isolate was aldehidetriterpenoide compounds which had functional group like –OH (3429 cm-1), -CH aldehyde (2922,9 and 2852,9 cm-1),-CºC- (2360 cm-1), -C=O (1742,7 cm-1), -C=C- alkene(1637,0 cm-1), -CH3, -CH2 (1542,9, 1480,7, 1401,9 cm-1), -CO-(1090 cm-1), It showed absorbed at broad peaks at l(nm) (CHCl3): 254, 282, and 342,7.”

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PDF:

https://jurnal.harianregional.com/jchem/full-2742

Published

2021-11-09

How To Cite

SANTI, Sri Rahayu. PENELUSURAN SENYAWA SITOTOKSIK PADA KULIT BIJI NYAMPLUNG (Calophyllum inophyllum L.) DAN KEMUNGKINAN KORELASINYA SEBAGAI ANTIKANKER.Jurnal Kimia (Journal of Chemistry), [S.l.], nov. 2012. ISSN 2599-2740. Available at: https://jurnal.harianregional.com/jchem/id-2742. Date accessed: 28 Aug. 2025.

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Issue

Vol. 3, No. 2 Juli 2009

Section

Articles

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