Authors:

I W. G. Gunawan, I G. A. Gede Bawa, N. L. Sutrisnayanti

Abstract:

“Isolation and identification of terpenoid, antibacterial compounds meniran herb (Phyllanthus niruri Linn) by GasChromatography – Mass Spectroscophy were carried out. Two kinds of extraction, i.e. maseration using methanoland the sochlet using n-hexane were employed.The extract obtained were contains terpenoids basedon fitochemical test of Liberman-Burchard n-hexaneextract was tested for antimicrobial activity against Escherichia coli ATCC® 25292 and Staphylococcus aureusATCC® 25293. In this study we obtained that n-hexane extract by sochlet extraction showed greater activitycompared to the extract by maseration with methanol, as indiated by disc diameter of inhibition zone. Diametricinhibition zone for these two extract are 1 mm for Escherichia coli and 0,5 mm for Staphylococcus aureus, formethanol extract, and where are 10 mm for Escherichia coli and 12 mm for Staphylococcus aureus for n-hexaneextract.The n-hexane extract was then purified using column chromatography. The pure extract was analyzed usingGas Chromatography - Mass Spectroscophy. Gas Chromatography - Mass Spectroscophy data indicated that theextract contains two compounds, i.e. phytadiene [ M+ ] 278 and 1,2 seco – cladiellan m/z 335 [ M+ - H ].”

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PDF:

https://jurnal.harianregional.com/jchem/full-2695

Published

2021-11-09

How To Cite

GUNAWAN, I W. G.; GEDE BAWA, I G. A.; SUTRISNAYANTI, N. L.. ISOLASI DAN IDENTIFIKASI SENYAWA TERPENOID YANG AKTIF ANTIBAKTERI PADA HERBA MENIRAN (Phyllanthus niruri Linn).Jurnal Kimia (Journal of Chemistry), [S.l.], nov. 2012. ISSN 2599-2740. Available at: https://jurnal.harianregional.com/jchem/id-2695. Date accessed: 28 Aug. 2025.

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Issue

Vol. 2, No. 1 Januari 2008

Section

Articles

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