Authors:

A. A. Tia Santika Dewi, Ni Made Puspawati, Putu Suarya

Abstract:

“Stem bark of Tenggulun (Protium javanicum, Burm) has been used traditionally by Balinese people as anti-inflammatory agents. This research aimed to analyze phytochemical contents and to evaluate anti-inflammatory activity of stem bark ether extract of Tenggulun. Phytochemical study was done qualitatively using phytochemical reagents. Anti-inflammatory activity was evaluated on edema rats induced by carrageenan with given extract at doses of 125, 250, and 500 mg/kg b.w. Diclophenac sodium was used as the positive control. Phytochemical study revealed that the stem bark ether extracts consisted of alkaloids, steroids, terpenoids, and phenolic compounds. Anti-inflammatory activity test results showed at a dose of 125 mg/kg b.w, the extract only inhibit inflammation by 34.54%, while a dose of 250 mg/kg b.w gave inhibition of inflammation by 94.34%, and a dose of 500 mg/kg b.w can inhibit inflammation by 96.11% during 360 minutes observation. Probit analysis gave ED50 value of 103.252 mg/kg B.W.”

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PDF:

https://jurnal.harianregional.com/jchem/full-15243

Published

2015-01-01

How To Cite

TIA SANTIKA DEWI, A. A.; PUSPAWATI, Ni Made; SUARYA, Putu. AKTIVITAS ANTIINFLAMASI EKSTRAK ETER KULIT BATANG TENGGULUN (Protium javanicum Burm) TERHADAP EDEMA PADA TIKUS WISTAR YANG DIINDUKSI DENGAN KARAGENAN.Jurnal Kimia (Journal of Chemistry), [S.l.], jan. 2015. ISSN 2599-2740. Available at: https://jurnal.harianregional.com/jchem/id-15243. Date accessed: 28 Aug. 2025. doi:https://doi.org/10.24843/JCHEM.2015.v09.i01.p03.

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ABNT, APA, BibTeX, CBE, EndNote - EndNote format (Macintosh & Windows), MLA, ProCite - RIS format (Macintosh & Windows), RefWorks, Reference Manager - RIS format (Windows only), Turabian

Issue

Vol. 9, no. 1 Januari 2015

Section

Articles

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License