Authors:

Claudia Anastasia, AA Ngurah Subawa

Abstract:

“ABSTRAK Stroke adalah kelainan neurologis yang merupakan salah satu penyebab utama kecacatanjangka panjang dan kematian di seluruh dunia. Menurut WHO, pada tahun 2012 diperkirakan terdapat6,7 juta orang meninggal akibat penyakit stroke sehingga penyakit ini menjadi salah satu dari 3penyebab utama hilangnya tahun-tahun kehidupan akibat mortalitas atau kematian dini. Asam uratyang merupakan hasil dari metabolisme putin dalam tubuh manusia ditemukan memiliki hubunganerat dengan beberapa faktor risiko penyakit kardiovaskuler yang juga menjadi faktor risiko penyakitstroke. Namun, hubungan antara keduanya masih kontroversial. Penelitian ini dilakukan denganmetode penelitian potong-lintang analitik menggunakan data sekunder untuk mengetahui hubunganantara kadar asam urat terhadap kejadian stroke iskemik di RSUP Sanglah. Sampel pada penelitian inidiambil dengan menggunakan cara consecutive sampling yang memenuhi kriteria inklusi dan eksklusihingga tercapai jumlah sampel yang diperlukan. Penelitian ini menggunakan data rekam medis daritahun 2016, dengan jumlah sampel sebanyak 25 orang untuk pasien kelompok kasus dan 25 oranguntuk pasien kelompok kontrol. Pada penelitian ini didapatkan bahwa rerata kadar asam uratkelompok kasus adalah 6,12±1,88 mg/dl dan lebih tinggi dibandingkan dengan kadar asam urat padakelompok kontrol (5,23±1,36 mg/dl). Rerata kadar asam urat pada pasien laki-laki (5,98±1,54 mg/dl)lebih tinggi dibandingkan dengan pasien perempuan (5,27±1,84 mg/dl). Namun pada uji chi-square,didapatkan bahwa tidak ada asosiasi yang signifikan antara kadar asam urat dengan kejadian strokeiskemik. Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa kadar asam urat tidak memilikihubungan yang signifikan terhadap kejadian stroke iskemik. Kata kunci: Stroke iskemik, kadar asam urat, RSUP Sanglah ABSTRACT Stroke is a neurological deficit that is one of the major causes of long-term disability andmortality all over the world. According to WHO, in 2012 approximately 6.7 million people diedbecause stroke, making this disease as one of the threee major causes of losing years of life because ofmortality and premature death. Uric acid, which is a result from purin metabolism in human’s body, isfound to have a correlation with some of cardiovascular diseases’ risk factors which is also risk factorsof stroke. But, the association between uric acid and stroke itself is remain controversial. This studywas an analytical cross-sectional study, using secondary data to find out the association betweenserum uric acid levels with ischemic stroke events in patients at RSUP Sanglah. Samples that wereused in this study was taken with consecutive sampling method for all the samples that were matchedto the inclusion and exclusion criterias until the minimal amount of the samples needed was reached.This study used medical records data in 2016 with 25 cases of ischemic stroke and 25 controls. In thisstudy, it was found that the mean serum uric acid in cases group was 6.12±1.88 mg/dl and was higherthan controls’ mean serum uric acid (5.23±1.36 mg/dl). Mean serum uric acid in men (5.98±1.54mg/dl) was higher in women (5.27±1.84 mg/dl). However, from Chi-square test, it was found thatthere was no significant association between serum uric acid level and ischemic stroke events. Basedon this study, we can conclude that serum uric acid has no significant association with ischemic strokeevents. Keywords: ischemic stroke, serum uric acid level, RSUP Sanglah”

Keywords

Stroke iskemik, kadar asam urat, RSUP Sanglah ABSTRACT Stroke is a neurological deficit that is one of the major causes of long-term disability andmortality all over the world. According to WHO, in 2012 approximately 6.7 million people diedbecause stroke, making this disease as one of the threee major causes of losing years of life because ofmortality and premature death. Uric acid, which is a result from purin metabolism in human’s body, isfound to have a correlation with some of cardiovascular diseases’ risk factors which is also risk factorsof stroke. But, the association between uric acid and stroke itself is remain controversial. This studywas an analytical cross-sectional study, using secondary data to find out the association betweenserum uric acid levels with ischemic stroke events in patients at RSUP Sanglah. Samples that wereused in this study was taken with consecutive sampling method for all the samples that were matchedto the inclusion and exclusion criterias until the minimal amount of the samples needed was reached.This study used medical records data in 2016 with 25 cases of ischemic stroke and 25 controls. In thisstudy, it was found that the mean serum uric acid in cases group was 6.12±1.88 mg/dl and was higherthan controls’ mean serum uric acid (5.23±1.36 mg/dl). Mean serum uric acid in men (5.98±1.54mg/dl) was higher in women (5.27±1.84 mg/dl). However, from Chi-square test, it was found thatthere was no significant association between serum uric acid level and ischemic stroke events. Basedon this study, we can conclude that serum uric acid has no significant association with ischemic strokeevents. Keywords: ischemic stroke, serum uric acid level, RSUP Sanglah

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PDF:

https://jurnal.harianregional.com/eum/full-62950

Published

2020-07-23

How To Cite

ANASTASIA, Claudia; SUBAWA, AA Ngurah. HUBUNGAN KADAR ASAM URAT TERHADAP KEJADIAN STROKE ISKEMIK DI RSUP SANGLAH TAHUN 2016.E-Jurnal Medika Udayana, [S.l.], v. 9, n. 7, p. 18-22, july 2020. ISSN 2303-1395. Available at: https://jurnal.harianregional.com/eum/id-62950. Date accessed: 02 Jun. 2025. doi:https://doi.org/10.24843/MU.2020.V09.i7.P04.

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Vol 9 No 7 (2020): Vol 9 No 07(2020): E-Jurnal Medika Udayana

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Articles

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