Authors:

Laskar Pradnyan Kloping, P. Purwati, Mouli Edward

Abstract:

“Background: Fractured bone healing requires three to nine months, which prolongs the patients’ morbidity. Long bone fracture is considered to be difficult due to the dependence of bodily mobility and freedom. Bone tissue engineering materials includes hydroxyapatite (HAp), titanium, alumina, and polymers. HAp is found to be heavily abundant in cuttlefish. This study is conducted to prove that the cuttlebone has an effect of accelerating the fractured long bone healing process. Methods: This is an experimental study using a total of 32 samples of Rattus norwegicus. The Treatment Group received the cuttlebone extract + 0.9% NaCl while the Control Group received only NaCL 0.9%. Both groups were fractured beforehand. On the 14th day the fractured area was harvested and assigned for histopathology and radiographic exam. Results: The Treatment Group was found to have thicker callus formation and more osteoblasts. Conclusions: The cuttlebone extract application caused thicker callus and higher osteoblast production, proving an accelerated fractured bone healing process.”

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PDF:

https://jurnal.harianregional.com/bmj/full-21795

Published

2016-04-30

How To Cite

KLOPING, Laskar Pradnyan; PURWATI, P.; EDWARD, Mouli. The Healing Effect of Cuttlefish Bone on Fractured Bone in Rat Model.BALI MEDICAL JOURNAL, [S.l.], v. 5, n. 2, apr. 2016. ISSN 2302-2914. Available at: https://jurnal.harianregional.com/bmj/id-21795. Date accessed: 28 Aug. 2025.

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Issue

Vol 5 No 2 (2016)

Section

Articles

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License