Dynamics of Human Mesenchymal Stem Cells, M1 Microglia/Macrophage, and Fractalkine in Ischemic Stroke Patients
on
Authors:
Lucia Herminawati, Andi Wijaya, Mansyur Arief, Suryani As’ad
Abstract:
“Background: About 85% of strokes are ischemic strokes, caused by occlusion of cerebral artery that induced brain inflammation. A deep understanding of ischemic stroke mechanism will lead to better neurorestorative treatment. Objective: This study investigates the dynamics of human mesenchymal stem cells, fractalkine, and M1 microglia/macrophage in ischemic stroke patients. Results: We found the same fractalkine levels and M1 microglia/macrophage cells on patients with stroke onset 0 to 14 days, then decrease until 30 days of stroke onset. MSCs was increase 7 days after stroke onset, peaked by 14 days, then decreased until 30 days after stroke ischemic onset. Conclusions: This study found an interaction between microglia/macrophage, fractalkine, and MSCs on ischemic stroke patients, so therapeutic strategy could be developed.”
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PDF:
https://jurnal.harianregional.com/bmj/full-21792
Published
2016-04-30
How To Cite
HERMINAWATI, Lucia et al. Dynamics of Human Mesenchymal Stem Cells, M1 Microglia/Macrophage, and Fractalkine in Ischemic Stroke Patients.BALI MEDICAL JOURNAL, [S.l.], v. 5, n. 1, apr. 2016. ISSN 2302-2914. Available at: https://jurnal.harianregional.com/bmj/id-21792. Date accessed: 28 Aug. 2025.
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Issue
Vol 5 No 1 (2016)
Section
Articles
Copyright
This work is licensed under a Creative Commons Attribution 4.0 International License
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