Authors:

Sarasmita M A, Setyawan E. I., Hendra Jaya A.

Abstract:

“Diabetes Mellitus (DM) is a metabolic disease with characteristics of hyperglycemia that occurs due to insulin secretion abnormalities, insulin work or both. DM can cause macrovascular complications such as hypertension. Administration of therapy may lead to hypoglycemic and hypokalemia that may increase the risk of impaired brain and heart. Objective: The purpose of this study to analyze the incidence of hypoglycemia and hypokalemia side effects in patients with diabetic hypertension using antidiabetes and antihypertensives. Method: The study was conducted retrospectively with retrospective patient medical records from January to December 2016. Blood and potassium blood glucose levels were measured as long as the patient was treated. Random and potassium blood glucose levels prior to therapy were compared with after therapy using paired t-test. Result : From the results of the study found 27 patients suffering from diabetic hypertension and get therapy. The value of changes in the patient’s random blood glucose level averaged 280.89 mg/dl to 189.15 mg/dl, which met the target of antidiabetic drug therapy, and no patients had hypoglycemia. From 27 patients, as many as 7 people did not get antihypertensive therapy. Three patients had hyperkalemia (serum potassium level > 5 mEq/L). The value of changes in blood potassium levels of patients averaged 4.74 mEq/L to 4.46 mEq/L, where no patients had hypokalemia. Conclusion : the occurrence of hypoglycemia and hyperkalemia were suspected due to side effect of insulin and antihypertensive drugs.”

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References

  • [1] American Diabetes Association, 2016. Standards of
  • Medical Care in Diabetes-2016. Diabetes Care.
  • Volume 39. Supplement 1. S57.
  • [2] PERKENI. 2011. Konsensus Pengelolaan dan
  • Pencegahan Diabetes Melitus Tipe 2 di Indonesia
    1. Jakarta: Perkumpulan Endokrinologi Indonesia.
  • [3] Suastika, Ketut, dkk. 2011. Prevalence of Obesity,
  • Metabolic Syndrome, Impaired Fasting Glycemia, and
  • Diabetes in Selected Villages of Bali, Indonesia.
  • Journal of the ASEAN Federation of Endocrine
  • Societies. Vol. 26, No.2. 159-162.
  • [4] American Diabetic Association. 2011. Living with
  • Diabetes: Complications, Available at:
  • http://www.diabetes.org/living-withdiabetes/
  • complications/pregnant-women/afterdelivery.
  • html. cited on: 25 April 2015
  • [5] Soelistijo, Soebagijo Adi, dkk. 2015. Konsensus
  • Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2
  • di Indonesia 2015. Jakarta: PB PERKENI.
  • [6] Kekenusa, John S., Budi T. Ratag dan Gloria
  • Wuwungan. 2013. Analisis Hubungan Antara Umur
  • dan Riwayat Keluarga Menderita DM dengan
  • Kejadian Penyakit DM Tipe 2 Pada Pasien Rawat
  • Jalan di Poliklinik Penyakit Dalam BLU RSUP Prof.
  • Dr. R.D Kandou Manado. Manado: Fakultas Kesehatan
  • Masyarakat Universitas Sam Ratulangi.
  • [7] Jelantik, I G M Geria dan Erna Hayati. 2014.
  • Hubungan Faktor Risiko Umur, Jenis Kelamin,
  • Kegemukan dan Hipertensi dengan Kejadian Diabetes
  • Melitus Tipe II di Wilayah Kerja Puskesmas Mataram.
  • Media Bina Ilmiah. Volume 8, No.1. 39-44
  • [8] Ludirdja, Jovita Secunda, Leonard Kencana, Katrin
  • Kurniawan, Michelle Prinka Adyana dan IGP Suka
  • Aryana. 2010. Rerata Durasi Penderita Diabetes
  • Melitus Terkena Nefropati Diabetik Sejak Terdiagnosis
  • Diabetes Melitus Pada Pasien di Poliklinik Geriatri
  • RSUP Sanglah. IPTEKMA. Volume 2 No.1. 15-19
  • [9] Saraswati, Ni Made Weda. 2009. Studi Penggunaan
  • Obat pada Pasien Diabetes Mellitus Tipe 2 dengan
  • Komplikasi Hipertensi di Unit Rawat Inap RSUP
  • Sanglah Denpasar Tahun 2008 (Skripsi). Bukit
  • Jimbaran: Jurusan Farmasi Fakultas MIPA Universitas
  • Udayana.
  • [10] Joint National Committee (JNC) VII. 2004. The
  • Seventh Report of the Joint National Committee on:
  • Prevention, Detection, Evaluation, and Treatment of
  • High Blood Pressure. United States: National Institutes
  • of Health.
  • [11] Haneda, Masakazu, dkk. 2015. A new Classification of
  • Diabetic Nephropathy 2014: a report from Joint
  • Committee on Diabetic Nephropathy. Journal of
  • Diabetes Investigation. Vol. 6. No.2. 242-246.
  • [12] Gross, Jorge L., De Azevedo, Mirela J., Silviero,
  • Sandra P., Canani, Luis Henrique, Caramori, Maria
  • Luiza dan Zelmanovitz, Themis. 2005. Diabetic
  • Nephropathy: Diagnosis, Prevention, and Treatment.
  • Diabetes Care. Volume 28, Number 1. 164-176.
  • [13] Joy, M.S., Kshirsagar, A., Paparello, J., 2005. Chronic
  • Kidney Disease: Progression-Modifying Therapies. In:
  • DiPiro, J. T., Talbert, R. L., Yee, G. C., Matzke, G. R.,
  • Wells, B. G., Posey, L. M., Pharmacotheraphy A
  • Pathophysiologic Approach, Ed 6th, New York:
  • McGraw Hill Medical Publishing Devision., p.799-820
  • [14] Rodriguez, Joyce C. Hollander., Calvert, James F.,
    1. Hyperkalemia. American Family Physician
  • Volume 73, No 2.www.aafp.org/afp., p. 283-290
  • [15] Brophy, D. F., Gehr T. W. B., 2005. Disorder of
  • Potassium and Magnesium Homeostasis. In: DiPiro, J.
  • T., Talbert, R. L., Yee, G. C., Matzke, G. R., Wells, B.
  • G., Posey, L. M., Pharmacotheraphy A
  • Pathophysiologic Approach, Ed 6th, New York:
  • McGraw Hill Medical Publishing Devision., p. 967-
  • 979
  • [16] Andayani, Esthi. 2008, Perubahan Kadar Gula Darah
  • Pasien Penyakit Gagal Ginjal Kronik pada Terapi
  • Hiperkalemia Dengan Insulin 2 Unit Dan Dextrose
  • 40% 25 ml,Tesis : Fakultas Farmasi Universitas
  • Airlangga, p.69-79

PDF:

https://jurnal.harianregional.com/jhsm/full-36986

Published

2018-01-25

How To Cite

A, Sarasmita M; I., Setyawan E.; A., Hendra Jaya. Occurrence of Hypoglycemia, Hypokalemia and Hyperkalemia in Diabetic Hypertensive Patients Using Insulin and Diuretics.Journal of Health Sciences and Medicine, [S.l.], v. 1, n. 2, p. 11-15, jan. 2018. ISSN 2622-0555. Available at: https://ojs.unud.ac.id/index.php/JHSM/article/view/36986. Date accessed: 28 Aug. 2025. doi:https://doi.org/10.24843/JHSM.2017.v01.i02.p04.

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Vol 1 No 2 (2017): JHSM (September 2017)

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Articles

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