ANTIOXIDANT ACTIVITY TEST OF ANDROGRAPHOLIDE IN BITTER HERBS USING DPPH SCAVENGING
on
Authors:
Ni Made Pitri Susanti, Ni Kadek Warditian, I Made Agus Gelgel Wirasuta
Abstract:
“Abstract Bitter herbs (Sambiloto) have many pharmacological activities including antioxidant, antidiabetic, anticancer, antihyperlipidemic and anti-inflammation. Andrographolide is a diterpene compounds contained in bitter herbs. It is known that andrographolide compound responsible for the pharmacological activity of the bitter herbs. This study investigated DPPH free radical scavenging activity from andrographolide diterpene lactone. This study was initiated with the isolation of andrographolide compound from bitter herbs and then testing their DPPH free radical scavenging. The results suggested that andrographolide had IC50 value of 5.45 mg. This means andrographolide has 50% DPPH inhibition effect, i.e 5.45 mg.”
Keywords
Keyword Not Available
Downloads:
Download data is not yet available.
References
- REFERENCES
- [1] Pietta P-G., 1999. Flavonoids as Antioxidants, Reviews, J. Nat.
- Prod., 63, 1035-1042
- [2] Wijaya A., 1996. Radikal Bebas dan Parameter Status Antioksidan,
- Forum Diagnosticum, Prodia Diagnostic Educational Services, No. 1
- : 1-12.
- [3] Leong L.P., Shui, G., 2001. An Investigation of Antioxidant Capacity
- of Fruits in Singapore Markets, Food Chemistry 76 : 69-75.
- [4] Clarkson, P. M., Thompson, H. S. 2000, Antioxidants: what role do
- they play in physical activity and health, J. Clin Nutr. Biochem, 72.:
- 637S-46S.
- [5] Prakash A., 2001. Antioxidant Activity, Medallion Laboratories
- Analytical Progress, Vol. 19 (2).
- [6] Okawa M., Kinjo, J., Nohara, T., Ono, M., 2001. DPPH (1,1-
- Diphenyl-2-Picrylhydrazyl) Radical Scavenging Activity of
- Flavonoids Obtained from Some Medicinal Plants, Biol. Pharm. Bull
- 24 (10), 1202-1205.
- [7] Huidrom, Sangeeta and Deka, Manab, 2012, Determination of
- antioxidant property of Andrographis paniculata, IJDAD, 1(1): 12-
- 17
PDF:
https://jurnal.harianregional.com/jhsm/full-34806
Published
2017-02-01
How To Cite
SUSANTI, Ni Made Pitri; WARDITIAN, Ni Kadek; WIRASUTA, I Made Agus Gelgel. ANTIOXIDANT ACTIVITY TEST OF ANDROGRAPHOLIDE IN BITTER HERBS USING DPPH SCAVENGING.Journal of Health Sciences and Medicine, [S.l.], v. 1, n. 1, p. 9-11, feb. 2017. ISSN 2622-0555. Available at: https://ojs.unud.ac.id/index.php/JHSM/article/view/34806. Date accessed: 02 Jun. 2025. doi:https://doi.org/10.24843/JHSM.2017.v01.i01.p03.
Citation Format
ABNT, APA, BibTeX, CBE, EndNote - EndNote format (Macintosh & Windows), MLA, ProCite - RIS format (Macintosh & Windows), RefWorks, Reference Manager - RIS format (Windows only), Turabian
Issue
Vol 1 No 1 (2017): JHSM (Febuary 2017)
Section
Articles
Copyright
This work is licensed under a Creative Commons Attribution 4.0 International License
Discussion and feedback