UPPER GASTROINTESTINAL MALIGNANCY IN PATIENTS UNDERGOING ESOPHAGOGASTRODUODENOSCOPY IN SANGLAH GENERAL HOSPITAL DENPASAR

Putu Prathiw Primadharsini*. Hendra Koncoro**. Luh Putu Iin Indrayani Maker***. Gde Somayana*, I Ketut Mariadi*, I Gusti Agung Suryadarma*, Nyoman Purwadi*. I DewaNyoman Wibawa*

♦Division OfGastroenterohepatology, **Department OfInternai Medicine, ♦♦♦Department OfPathology and Anatomy, Udayana UniversityZSanglah General Hospital, Denpasar

ABSTRACT

Background: Upper gastrointestinal (UGI) malignancy is one of major causes of cancer related death. However, data of UGI malignancy in Indonesian health care center were limited. This study was aimed to determine the prevalence of UGI malignancy in patients undergoing esophagogastroduodenoscopy in Sanglah General Hospital Denpasar.

Methods: A retrospective study was conducted on 780 patients who had esophagogastroduodenoscopy in Endoscopy Unit of Sanglah General Hospital Denpasar between June 2012 and May 2014. Demographic, endoscopic and histopathological findings were documented.

Results: Of 780 patients undergoing esophagogastroduodenoscopy. 46 (5.9%) were confirmed with UGI malignancy. Thirty one (67.4%) patients were male. The mean age was 55.91 ± 10.995 years. Of 46 UGI malignancy patients, 25 (54.3%) had gastric cancer, 14 (30.4%) with esophageal cancer, and 7 (15.2%) had duodenal cancer. From histopathological findings, 19 patients (41.3%) had adenocarcinoma gaster, 5 (10.9%) with signet ring carcinoma of gaster, 3 (6.5%) with GIST, 7 (15.2%) with adenocarcinoma of esophagus. 5 (10.9%) with squamous cell carcinoma of esophagus, and 7 (15.2%) with adenocarcinoma of duodenum. Thirteen (52%) cases of gastric cancer were located in anthrum and 9 (36%) were located in corpus.

Conclusions: UGI malignancy was found in 5.9% undergoing esophagogastroduodenoscopy in Sanglah General Hospital Denpasar. The most frequent UGI malignancy was gastric cancer; while adenocarcinoma was the most frequent type of gastric cancer.

Keywords: esophagogastroduodenoscopy; upper gastrointestinal malignancy

IkllilVllUlN 1 H∣JX1A1∖ IklliOrjriAlAl^lM DIREKTORAT JENDERAL BINA UPAYA KESEHATAN RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR

Jalan Diponegoro Denpasar Bali (80114)

Telepon. (0361)227911-15,225482, 223869, Faximile. (0361) 224206

Email: info@sanglahhospitalbali.com, Website : www.sanglahhospitalbali.com

SURAT MtN

Nomor: LB.02.01/ll.C5.D11/ 7900 /2014

Sehubungan dengan surat Keterangan Komisi Etik (Ethical Clearance) Ketua Komisi Etik Penelitian Fakultas Kedokteran Universitas UdayanaZRSUP Sanglah Denpasar Nomor: 810∕UN.14.2∕Litbang∕2014 tertanggal 06 Juni 2014 kami mengijinkan Saudara atas nama:

Peneliti Utama : dr. Hendra Koncoro

Peneliti Lain : dr. I Ketut Mariadi₁ Sp. PD

Prof. Dr. dr. I.D.N. Wibawa, Sp.PD-KGEH dr. Luh Putu Iin Indrayani Maker, Sp. PA

Bag/SMF : Ilmu Penyakit Dalam FK UNUD/RSUP Sanglah Denpasar.

Untuk melakukan penelitian tentang ^aInsidensi Keganasan Saluran Cerna Bagian Atas di RS Sanglah Denpasar”

Setelah melakukan penelitian yang bersangkutan diwajibkan mengumpulkan 1 (satu) exemplar dan 1 (satu) soft copy hasil penelitian di Bagian Dikiit RSUP Sanglah Denpasar.

Demikian surat ijin ini kami buat untuk dipergunakan sebagaimana mestinya.

Pendidikan

Ugroho, M.Kes

NIP. 19580119198410 1002

Tembusan:

1. Ka. Bag/SMF Ilmu Penyakit Dalam FK UNUD/RSUP Sanglah Denpasar
2. Ka. Instalasi Patologi Anatomi RSUP Sanglah Denpasar.
3. Ka. Bag/SMF Patologi Anatomi FK UNUD/RSUP Sanglah Denpasar.
4. Yang bersangkutan.

Kementerian kesehatan ri DIREKTORAT JENDERAL BINA UPAYA KESEHATAN RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR

JaIan Diponegoro Denpasar BaIi (80114)

Telepon. (0361) 227911-15, 225482, 223869, Faximile. (0361) 224206

Email: info@saiiglahhospitalbaii.com, Website : www.sanglahhospitalbali.com

SURAT IJIN

Nomor: LB.02.01/II.C5.D11/ 7900 /2014

Peneliti Utama : dr. Hendra Koncoro

Peneliti Lain : dr. I Ketut Mariadi₁ Sp.PD

Prof. Dr. dr. I.D.N. Wibawa, Sp.PD-KGEH dr. Luh Putu Iin Indrayani Maker, Sp.PA

BagZSMF : Ilmu Penyakit Dalam FK UNUD/RSUP Sanglah Denpasar.

Untuk melakukan penelitian tentang ^uInsidensi Keganasan Saluran Cerna Bagian Atas di RS Sanglah Denpasar”

Setelah melakukan penelitian yang bersangkutan diwajibkan mengumpulkan 1 (satu) exemplar dan 1(satu) soft copy hasil penelitian di Bagian Diklit RSUP Sanglah Denpasar.